Pathophysiology of Autoimmune Bullous Diseases
نویسندگان
چکیده
منابع مشابه
Pathophysiology of Autoimmune Bullous Diseases: Nature Versus Nurture
Pemphigus and pemphigoid are the prototypical immunobullous diseases. Although it has been well established that they are caused by deposition of autoreactive antibodies directed against adherence proteins within the skin, the specific genetic and environmental factors leading to development of these diseases continue to be an area of investigation. Herein, we discuss several of the potential e...
متن کاملImmunofluorescence Pattern of Autoimmune Bullous Diseases in Iranian Patients
Background & Objective: Autoimmune bullous diseases are associated with autoimmunity against structural components in the skin and mucous membranes. Autoantibodies are against the intercellular junctions in pemphigus disease and hemidesmosomal unchoring complex in pemphigiod diseases and epidermolysis bullosa aquisita. The tissue-bound and circulating serum autoantibodies can be detect...
متن کاملTherapy of autoimmune bullous diseases
Autoimmune bullous diseases result from an immune response to molecular components of the desmosome or basement membrane. Bullous diseases are associated with a high degree of morbidity and occasional mortality. Therapy of bullous diseases consists of suppressing the immune system, controlling inflammation and improving healing of erosions. The therapeutic agents used in the treatment of bullou...
متن کاملDiagnosis and Pathophysiology of Bullous Diseases
From the Department of Dermatology, University of Cincinnati. Reprint requests: Diya F. Mutasim, MD, Department of Dermatology, University of Cincinnati, PO Box 670592, Cincinnati, OH 452670592. E-mail: [email protected]. Copyright © 2001 by the American Academy of Dermatology, Inc. 0190-9622/2001/$35.00 + 0 16/2/117518 doi:10.1067/mjd.2001.117518 I mmunofluorescence has been used for 4 dec...
متن کاملThe Spectrum of Autoimmune Bullous Diseases
Autoimmune bullous diseases are a group of cutaneous disorders characterised by skin blistering or erosions as a result of development of autoimmunity. It can be classified according to the anatomical sites of blister into two types: intraepithelial and subepidermal. It can be subdivided further according to the clinical features, type and location of immunoreactants found on skin biopsy (Table...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2008
ISSN: 0022-202X
DOI: 10.1038/skinbio.2008.4